Wednesday, April 18, 2018

IGV's translation row gets frameshifted when scrolling

The Integrated Genomics Viewer (IGV) can show the translation of the DNA if the "show translation" option is checked in the context menu of the sequence band at the bottom. It shows three different possible translations, one for each reading frame. I have noticed, though, that which band is which reading frame can get jumbled when moving the viewport, especially when clicking the top navigation band to jump. Therefore, figuring out which band is the helpful one has to be redone after scrolling around. In most cases, there should be at least one nearby stop codon in the frame of the wrong bands, making it clear that they're probably not the ones to look at.

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